Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | CD69 | Q07108 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10830385 | 0.80 | MAPT (0.34) | KMT2AMAPTKDM4EALDH1A1POLB | |
| SCHEMBL10660735 | 0.80 | KMT2A (0.37) | KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL10829666 | 0.77 | KMT2A (0.39) | KMT2AMAPTKDM4EALDH1A1PTGDR2 | |
| SCHEMBL10829999 | 0.77 | MAPT (0.39) | KMT2AMAPTALDH1A1PTGDR2CD69 | |
| SCHEMBL10660703 | 0.74 | KMT2A (0.40) | KMT2AMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL10829981 | 0.74 | MAPT (0.39) | KMT2AMAPTKDM4EALDH1A1CD69 | |
| SCHEMBL10829798 | 0.72 | MAPT (0.34) | KMT2AMAPT | |
| SCHEMBL10830430 | 0.72 | MAPT (0.34) | KMT2AMAPT | |
| SCHEMBL10829993 | 0.72 | ALDH1A1 (0.41) | KMT2AKDM4EALDH1A1PTGDR2CD69 | |
| SCHEMBL10829772 | 0.71 | MAPT (0.35) | KMT2AMAPTPSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4569938-A | Diuretic, antihypertensive and antihistaminic 7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1986-02-11 | — | — | US | disclosed |