SCHEMBL10830583

SCHEMBL10830583

Nc1csc(C(=O)[C]=O)n1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.34
PLK3 Q9H4B4 1/20 0.34
GABRA5 P31644 1/20 0.32
GABRB2 P47870 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19329267 0.77
SCHEMBL1047944 0.77
SCHEMBL11404925 0.77
SCHEMBL7770763 0.76 HSD17B10 (0.44) CSNK2A1PLK3HSD17B10
SCHEMBL27390219 0.75
SCHEMBL10922090 0.75
Lithium SCHEMBL31223951 0.75 CSNK2A1 (0.40) CSNK2A1PLK3GABRA5GABRB2HSD17B10
SCHEMBL10866605 0.75
SCHEMBL8973779 0.73 CSNK2A1 (0.39) CSNK2A1PLK3GABRA5GABRB2HSD17B10
SCHEMBL4788606 0.72 GRM5 (0.40) CSNK2A1PLK3GABRA5GABRB2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4563450-A CEPHALOSPORINS, MICROBIOCIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-01-07 US disclosed
EP-0033965-B1 NEW CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-05-15 EP disclosed
EP-0126859-A1 Intermediate compounds for preparing cephem compounds and processes for their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-12-05 EP disclosed
US-4405617-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-09-20 US disclosed
US-4350694-A OXACEPHALOSPORINS/; FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-09-21 US disclosed
EP-0033965-A2 New cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-08-19 EP disclosed
US-4234724-A OXADETHIACEPHEMCARBOXYLIC ACIDS FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1980-11-18 US disclosed