Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | KDM4B | O94953 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1047944 | 0.83 | — | — | |
| Lithium SCHEMBL31223951 | 0.81 | CSNK2A1 (0.40) | CSNK2A1PLK3GABRA5GABRB2HSD17B10 | |
| SCHEMBL19329267 | 0.78 | — | — | |
| SCHEMBL11404925 | 0.78 | — | — | |
| SCHEMBL9814252 | 0.77 | ALDH1A1 (0.40) | CSNK2A1PLK3GABRA5GABRB2HSD17B10 | |
| SCHEMBL9814249 | 0.77 | ALDH1A1 (0.40) | CSNK2A1PLK3GABRA5GABRB2HSD17B10 | |
| SCHEMBL10505192 | 0.77 | CSNK2A1 (0.35) | CSNK2A1PLK3GABRA5GABRB2HSD17B10 | |
| SCHEMBL10922090 | 0.77 | — | — | |
| SCHEMBL10866605 | 0.77 | — | — | |
| SCHEMBL27390219 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041655-B1 | 2-(2-AMINO-THIAZOL-4-YL)-N-(IMIDAZOLIDIN AND PERHYDRO-1,3-DIAZIN-2-ON-1-YL)-2-IMINOACETYLCEPHALOSPORINS OF THE SYN-FORM, AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1984-07-25 | — | — | EP | claimed |
| EP-0041655-A2 | 2-(2-Amino-thiazol-4-yl)-N-(imidazolidin and perhydro-1,3-diazin-2-on-1-yl)-2-iminoacetylcephalosporins of the syn-form, and process for their preparation | BAYER AG (DE) | 1981-12-16 | — | — | EP | claimed |
| US-5585485-A | Cephalosporin intermediate products | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1996-12-17 | — | — | US | disclosed |
| US-5484928-A | 2-(2-aminothiazol-4-yl)-2-oxoacetic acid derivatives | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1996-01-16 | — | — | US | disclosed |
| EP-0312844-B1 | Cephalosporin intermediates, process for their preparation and their use | BIOCHEMIE GMBH (AT) | 1994-06-22 | — | — | EP | disclosed |
| EP-0185679-B1 | INTERMEDIARY PRODUCTS OF CEPHALOSPORINE, PREPARATION PROCESS THEREOF AND UTILIZATION THEREOF | BIOCHEMIE Gesellschaft m.b.H. (AT) | 1991-08-28 | — | — | EP | disclosed |
| EP-0423837-A2 | Cephalosporin intermediates and their utilisation | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1991-04-24 | — | — | EP | disclosed |
| EP-0312844-A1 | Cephalosporin intermediates, process for their preparation and their use | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1989-04-26 | — | — | EP | disclosed |
| EP-0086556-B1 | PROCESS FOR PREPARING (3S)-3-(((2-AMINO-4-THIAZOLYL)((1-CARBOXY-1-METHYLETHOXY)IMINO)-ACETYL)AMINO)-2-OXO-1-AZETIDINESULFONIC ACID AND 4-SUBSTITUTED DERIVATIVES | E.R. Squibb & Sons, Inc. (US) | 1986-05-07 | — | — | EP | disclosed |
| WO-1985004659-A1 | INTERMEDIARY PRODUCTS OF CEPHALOSPORINE, PREPARATION PROCESS THEREOF AND UTILIZATION THEREOF | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1985-10-24 | — | — | WO | disclosed |
| EP-0041655-B1 | 2-(2-AMINO-THIAZOL-4-YL)-N-(IMIDAZOLIDIN AND PERHYDRO-1,3-DIAZIN-2-ON-1-YL)-2-IMINOACETYLCEPHALOSPORINS OF THE SYN-FORM, AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4443374-A | Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]-acetyl]amino]-2-oxo-1-azetidinesulfonic acid, and 4-substituted derivatives | E. R. SQUIBB & SONS, INC. (US) | 1984-04-17 | — | — | US | disclosed |
| EP-0086556-A1 | Process for preparing (3S)-3-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)-acetyl)amino)-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives | E.R. Squibb & Sons, Inc. (US) | 1983-08-24 | — | — | EP | disclosed |
| EP-0041655-A2 | 2-(2-Amino-thiazol-4-yl)-N-(imidazolidin and perhydro-1,3-diazin-2-on-1-yl)-2-iminoacetylcephalosporins of the syn-form, and process for their preparation | BAYER AG (DE) | 1981-12-16 | — | — | EP | disclosed |