Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL653745 | 1.00 | PYGL (0.33) | PYGLMME | |
| SCHEMBL661038 | 0.91 | MME (0.35) | PYGLMME | |
| SCHEMBL659719 | 0.91 | MME (0.35) | PYGLMME | |
| SCHEMBL659720 | 0.91 | MME (0.35) | PYGLMME | |
| SCHEMBL994219 | 0.91 | MME (0.35) | PYGLMME | |
| SCHEMBL653065 | 0.91 | MME (0.35) | PYGLMME | |
| SCHEMBL655002 | 0.88 | CTSA (0.38) | MME | |
| SCHEMBL655001 | 0.88 | CTSA (0.38) | MME | |
| SCHEMBL650255 | 0.87 | MME (0.40) | PYGLMME | |
| SCHEMBL653395 | 0.84 | MME (0.40) | PYGLMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451782-A1 | DUAL-ACTING PYRAZOLE ANTIHYPERTENSIVE AGENTS | Theravance, Inc. (US) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011005674-A1 | DUAL-ACTING PYRAZOLE ANTIHYPERTENSIVE AGENTS | THERAVANCE, INC. (US) | 2011-01-13 | — | — | WO | disclosed |