⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21484286 | 0.80 | — | — | |
| SCHEMBL28674070 | 0.79 | — | — | |
| SCHEMBL11188063 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL21056168 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL31396169 | 0.77 | — | — | |
| SCHEMBL8773032 | 0.77 | ALDH1A1 (0.43) | — | |
| SCHEMBL21072040 | 0.77 | — | — | |
| SCHEMBL14941932 | 0.77 | TP53 (0.31) | — | |
| SCHEMBL1940675 | 0.76 | — | — | |
| SCHEMBL8773026 | 0.75 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11723980-B2 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-08-15 | — | — | US | disclosed |
| EP-4090658-A1 | THERAPEUTIC AGENTS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-11-23 | — | — | EP | disclosed |
| EP-3731869-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2020-11-04 | — | — | EP | disclosed |
| CN-102210054-B | Electrolyte having eutectic mixture and nitrile compound and electrochemical device containing the same | 株式会社LG化学 | 2018-09-07 | — | — | CN | disclosed |
| EP-2968381-A1 | SUGAR-LINKER-DRUG CONJUGATES | Hecht, Sidney (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014145109-A1 | SUGAR-LINKER-DRUG CONJUGATES | ARIZONA BOARD OF REGENTS, FOR AND ON BEHALF OF, ARIZONA STATE UNIVERSITY (US) | 2014-09-18 | — | — | WO | disclosed |
| EP-0083764-B1 | PROCESS FOR THE PREPARATION OF CARBAMATES | BASF Aktiengesellschaft (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0083764-A2 | Process for the preparation of carbamates | BASF Aktiengesellschaft (DE) | 1983-07-20 | — | — | EP | disclosed |
| US-4331438-A | TREATMENT WITH A FORMALDEHYDE ACCEPTOR | BASF WYANDOTTE CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |