Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837256 | 0.67 | — | — | |
| SCHEMBL50015 | 0.63 | — | — | |
| SCHEMBL10856138 | 0.61 | — | — | |
| SCHEMBL8855709 | 0.61 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL8764153 | 0.61 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL8762262 | 0.59 | — | — | |
| SCHEMBL450056 | 0.59 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL8764051 | 0.59 | — | — | |
| SCHEMBL5005529 | 0.57 | — | — | |
| SCHEMBL10859437 | 0.55 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4609748-A | PREPARATION OF TETRAHYDROQUINOLINE-8-NITRILES, AMIDES AND THIOAMIDES | JOHN WYETH & BROTHER, LTD. (GB) | 1986-09-02 | — | — | US | claimed |
| US-4577022-A | Silyl compounds | JOHN WYETH & BROTHER, LTD. (GB) | 1986-03-18 | — | — | US | claimed |
| US-4526970-A | Reacting tetrahydroquinoline sodium, potassium, lithium, or magnesium compound with silyl compound, subjecting product to hydrolysis or alcoholysis | JOHN WYETH & BROTHER LIMITED (GB) | 1985-07-02 | — | — | US | claimed |
| US-4609748-A | PREPARATION OF TETRAHYDROQUINOLINE-8-NITRILES, AMIDES AND THIOAMIDES | JOHN WYETH & BROTHER, LTD. (GB) | 1986-09-02 | — | — | US | disclosed |
| US-4577022-A | Silyl compounds | JOHN WYETH & BROTHER, LTD. (GB) | 1986-03-18 | — | — | US | disclosed |
| US-4526970-A | Reacting tetrahydroquinoline sodium, potassium, lithium, or magnesium compound with silyl compound, subjecting product to hydrolysis or alcoholysis | JOHN WYETH & BROTHER LIMITED (GB) | 1985-07-02 | — | — | US | disclosed |