Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10836562 | 0.91 | NPC1 (0.37) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL10835401 | 0.84 | CYP19A1 (0.39) | ALDH1A1KDM4EHPGDGAANPC1 | |
| SCHEMBL8777656 | 0.81 | GAA (0.38) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL8777753 | 0.80 | CNR2 (0.42) | ALDH1A1KDM4ECNR1CNR2MAPK1 | |
| SCHEMBL10834701 | 0.79 | CYP19A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL10836556 | 0.78 | GAA (0.39) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL8777570 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL8777527 | 0.74 | CYP19A1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL8777654 | 0.74 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL10834702 | 0.74 | NPC1 (0.34) | ALDH1A1KDM4EHPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618684-A | Substituted indoles | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-10-21 | — | — | US | disclosed |
| US-4485242-A | PRESSURE SENSITIVE CARBONLESS REPRODUCTION | STERLING DRUG INC. (US) | 1984-11-27 | — | — | US | disclosed |
| US-4307898-A | INDOLES | STERLING DRUG INC. (US) | 1981-12-29 | — | — | US | disclosed |
| EP-0035774-A2 | Indoles, process for preparing them and duplicating or marking systems containing them | STERLING DRUG INC. (US) | 1981-09-16 | — | — | EP | disclosed |