Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777552 | 0.94 | CYP19A1 (0.43) | CYP19A1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL10835395 | 0.91 | CYP19A1 (0.40) | CYP19A1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL8777790 | 0.88 | CYP19A1 (0.43) | CYP19A1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL8777527 | 0.87 | CYP19A1 (0.42) | CYP19A1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL10834701 | 0.85 | CYP19A1 (0.41) | CYP19A1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL10836556 | 0.84 | GAA (0.39) | ALDH1A1MAPTHTTNPSR1KDM4E | |
| SCHEMBL8777632 | 0.83 | CYP19A1 (0.39) | CYP19A1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL10835401 | 0.83 | CYP19A1 (0.39) | CYP19A1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL10729723 | 0.83 | CYP19A1 (0.44) | CYP19A1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL9657922 | 0.83 | ALDH1A1 (0.48) | CYP19A1ALDH1A1MAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618684-A | Substituted indoles | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-10-21 | — | — | US | disclosed |
| US-4485242-A | PRESSURE SENSITIVE CARBONLESS REPRODUCTION | STERLING DRUG INC. (US) | 1984-11-27 | — | — | US | disclosed |
| US-4307898-A | INDOLES | STERLING DRUG INC. (US) | 1981-12-29 | — | — | US | disclosed |
| EP-0035774-A2 | Indoles, process for preparing them and duplicating or marking systems containing them | STERLING DRUG INC. (US) | 1981-09-16 | — | — | EP | disclosed |