SCHEMBL108347

SCHEMBL108347

C=CC(=O)NCC(C)NC(=O)C=C

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
ALDH1A1 P00352 2/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
ACACB O00763 2/20 0.38
TGM2 P21980 1/20 0.38
CYP2C19 P33261 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ATM Q13315 1/20 0.33
CYP2D6 P10635 1/20 0.32
CNR2 P34972 2/20 0.32
PPARG P37231 2/20 0.32
PPARD Q03181 2/20 0.32
PPARA Q07869 2/20 0.32
CNR1 P21554 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylamide SCHEMBL7165132 0.93 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL18559656 0.86 TSHR (0.45) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28707554 0.83 TSHR (0.56) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28708233 0.83 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL24495938 0.81 TSHR (0.44) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL19860715 0.80 TSHR (0.62) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL18755013 0.80 TSHR (0.54) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL372689 0.80
SCHEMBL9726142 0.80 TSHR (0.52) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL8977572 0.80 TSHR (0.45) TSHRALDH1A1MAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 851 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12312595-B2 Hydrogel particles as feeder cells and as synthetic antigen presenting cells SLINGSHOT BIOSCIENCES, INC. (US) 2025-05-27 US claimed
CN-119907921-A Engineered particles as red blood cell mimics for hematology and compositions containing the same 弹弓生物科学公司 2025-04-29 CN claimed
US-20250122414-A1 THERMALLY STABLE ADDITIVE FOR WELLBORE TREATMENTS HALLIBURTON ENERGY SERVICES, INC. 2025-04-17 US claimed
WO-2025080281-A1 THERMALLY STABLE ADDITIVE FOR WELLBORE TREATMENTS HALLIBURTON ENERGY SERVICES, INC. (US) 2025-04-17 WO claimed
WO-2025080385-A1 THERMALLY STABLE ADDITIVE FOR WELLBORE TREATMENTS HALLIBURTON ENERGY SERVICES, INC. (US) 2025-04-17 WO claimed
US-20250122417-A1 THERMALLY STABLE ADDITIVE FOR WELLBORE TREATMENTS HALLIBURTON ENERGY SERVICES , INC. 2025-04-17 US claimed
US-20250011712-A1 HYDROGEL PARTICLES AS FEEDER CELLS AND AS SYNTHETIC ANTIGEN PRESENTING CELLS SLINGSHOT BIOSCIENCES, INC. (US) 2025-01-09 US claimed
US-20240425742-A1 High Temperature Suspension Additive For Wellbore Treatments HALLIBURTON ENERGY SERVICES, INC. (US) 2024-12-26 US claimed
WO-2024263211-A1 HIGH TEMPERATURE SUSPENSION ADDITIVE FOR WELLBORE TREATMENTS HALLIBURTON ENERGY SERVICES, INC. (US) 2024-12-26 WO claimed
CN-119000831-A CO based on hydrogel structure2Gas sensor, method for producing the same and use thereof 华东理工大学 2024-11-22 CN claimed
EP-1322408-A1 MEMBRANES AND METHOD OF MANUFACTURE THEREOF GRADIPORE LIMITED (AU) 2003-07-02 EP claimed
US-6551684-B1 Substrate with interstitial gaps having polymeric membrane within the gaps that are thinner than the cross-sectional thickness of the substrate GRADIPORE LIMITED (AU) 2003-04-22 US claimed
WO-2002013956-A1 MEMBRANES AND METHOD OF MANUFACTURE THEREOF GRADIPORE LIMITED (AU) 2002-02-21 WO claimed
EP-0606742-B1 Bile acid sequestrant ROHM & HAAS (US) 1997-11-19 EP claimed
US-5451397-A Crosslinked amino functional acrylic amide polymer, reducing blood cholesterol levels ROHM AND HAAS COMPANY (US) 1995-09-19 US claimed
EP-0606742-A1 Bile acid sequestrant ROHM AND HAAS COMPANY (US) 1994-07-20 EP claimed
US-5306404-A Mixing into gel supporter an acrylamide monomer, a cross-linking agent, a peroxide, and a reducing agent DAIICHI PURE CHEMICALS CO., LTD. (JP) 1994-04-26 US claimed
US-4963243-A POLYACRYLAMIDE GEL CONTAINING A WATER SOLUBLE POLYMER AND AGAROSE; DNA, RNA SEQUENCE DETERMINATION DIRECTOR OF THE FINANCE DIVISION MINISTER'S SECRETARIAT SCIENCE AND TECHNOLOGY AGENCY (JP) 1990-10-16 US claimed
US-4791061-A PRECIPITATION OF WATER INSOLUBLE ALOINATE, POLYMERIZATION OF ACRYLAMIDE HITACHI PLANT ENGINEERING & CONSTRUCTION CO., LTD. (JP) 1988-12-13 US claimed
US-4547463-A Method of immobilizing microorganisms NIPPON OIL COMPANY, LTD. (JP) 1985-10-15 US claimed