SCHEMBL28708233

SCHEMBL28708233

C=CC(=O)NCC(C)NC

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
ALDH1A1 P00352 2/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
TGM2 P21980 1/20 0.38
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
CNR2 P34972 4/20 0.32
PPARG P37231 2/20 0.32
PPARD Q03181 2/20 0.32
PPARA Q07869 2/20 0.32
CNR1 P21554 2/20 0.32
GAA P10253 1/20 0.30
ACACB O00763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108347 0.83 TSHR (0.56) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL6684683 0.81 TSHR (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL18755013 0.80 TSHR (0.54) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL372689 0.80
SCHEMBL8977572 0.80 TSHR (0.45) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL18559656 0.79 TSHR (0.45) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL14901 0.78
SCHEMBL17267140 0.78
SCHEMBL7744606 0.78 TSHR (0.52) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL10350868 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4623014-A1 DC POWER CABLE INSULATION SABIC Global Technologies B.V. (NL) 2025-10-01 EP claimed
WO-2025125020-A1 AN ADHESIVE COMPOSITION CONTAINING POLYETHYLENE BASED IONOMERS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-06-19 WO claimed
US-12269905-B2 Copolymer of ethylene and ion pair compound SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-04-08 US claimed
WO-2024110328-A1 DC POWER CABLE INSULATION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-05-30 WO claimed
US-20220259340-A1 COPOLYMER OF ETHYLENE AND ION PAIR COMPOUND SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-08-18 US claimed
EP-3999562-A1 COPOLYMER OF ETHYLENE AND ION PAIR COMPOUND SABIC Global Technologies, B.V. (NL) 2022-05-25 EP claimed
CN-114269797-A Copolymers of ethylene and ion-pair compounds SABIC环球技术有限责任公司 2022-04-01 CN claimed
EP-4623014-A1 DC POWER CABLE INSULATION SABIC Global Technologies B.V. (NL) 2025-10-01 EP disclosed
WO-2025125020-A1 AN ADHESIVE COMPOSITION CONTAINING POLYETHYLENE BASED IONOMERS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-06-19 WO disclosed
WO-2025125045-A1 ARTICLES CONTAINING POLYETHYLENE BASED IONOMERS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-06-19 WO disclosed
EP-3999562-A1 COPOLYMER OF ETHYLENE AND ION PAIR COMPOUND SABIC Global Technologies, B.V. (NL) 2022-05-25 EP disclosed
CN-114269797-A Copolymers of ethylene and ion-pair compounds SABIC环球技术有限责任公司 2022-04-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12269905-B2 Copolymer of ethylene and ion pair compound OR10J3, ETV6, H1-10 TSHR 2388/4885ALDH1A1 4237/4885MAPK1 2577/4885
US-20220259340-A1 COPOLYMER OF ETHYLENE AND ION PAIR COMPOUND OR10J3, ESR1, ETV6 TSHR 1338/4885ALDH1A1 4191/4885MAPK1 2575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.