Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | B3GNT2 | Q9NY97 | 2/20 | 0.37 |
| ▸ | GCK | P35557 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10834119 | 0.81 | POLB (0.66) | POLBMEN1CYP1A2KMT2AHPGD | |
| SCHEMBL30838374 | 0.74 | POLB (1.00) | POLBMEN1CYP1A2KMT2AHPGD | |
| SCHEMBL828232 | 0.74 | POLB (1.00) | POLBMEN1CYP1A2KMT2AHPGD | |
| SCHEMBL7443237 | 0.72 | POLB (0.70) | POLBMEN1CYP1A2KMT2AHPGD | |
| SCHEMBL10833903 | 0.72 | POLB (0.70) | POLBMEN1CYP1A2KMT2AHPGD | |
| SCHEMBL10736441 | 0.71 | POLB (0.74) | POLBMEN1CYP1A2KMT2AHPGD | |
| SCHEMBL904825 | 0.71 | POLB (0.74) | POLBMEN1CYP1A2KMT2AHPGD | |
| SCHEMBL7017890 | 0.71 | POLB (0.74) | POLBMEN1CYP1A2KMT2AHPGD | |
| SCHEMBL7513143 | 0.71 | POLB (0.68) | POLBMEN1CYP1A2KMT2AHPGD | |
| SCHEMBL14622076 | 0.70 | POLB (0.67) | POLBMEN1CYP1A2KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4604468-A | ADRENERIC BLOCKING AGENTS, ANTIDEPRESSANT | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 1986-08-05 | — | — | US | disclosed |
| US-4381309-A | ADRENERGIC BLOCKING AGENTS; ANTIDEPRESSANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1983-04-26 | — | — | US | disclosed |
| US-4343800-A | ANTIDEPRESSANTS; ADRENERGIC BLOCKING, HYPOTENSIVE, AND ANTIARRHYTHMIA AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-10 | — | — | US | disclosed |
| US-4296117-A | ADRENERGIC BLOCKING AGENTS, ANTIDEPRESSANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1981-10-20 | — | — | US | disclosed |
| US-4256756-A | ADRENERGIC BLOCKING AGENTS, ANTIDEPRESSANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1981-03-17 | — | — | US | disclosed |
| US-4255430-A | ANDRENERGIC RECEPTOR BLOCKING AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1981-03-10 | — | — | US | disclosed |
| US-4212877-A | ANTIDEPRESSANTS, ADRENERGIC BLOCKING AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-07-15 | — | — | US | disclosed |