Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.42 |
| ▸ | APEX1 | P27695 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10834938 | 1.00 | PTGS1 (0.47) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL10834350 | 0.92 | NR1I2 (0.42) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL10834352 | 0.92 | NR1I2 (0.42) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL6362891 | 0.91 | PTGS1 (0.55) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL6362892 | 0.91 | PTGS1 (0.55) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL10762469 | 0.91 | MAPT (0.53) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL11283553 | 0.89 | PTGS1 (0.47) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL11283556 | 0.89 | PTGS1 (0.47) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL10850361 | 0.87 | PTGS1 (0.48) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL10850349 | 0.87 | PTGS1 (0.48) | PTGS1NR1I2HTR2CABCB11PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4608373-A | BACTERICIDES, ANTIBIOTICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-08-26 | — | — | US | disclosed |
| EP-0112164-A2 | Cephem compounds, and their production, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-06-27 | — | — | EP | disclosed |