Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | APEX1 | P27695 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6362892 | 1.00 | PTGS1 (0.55) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL11283556 | 0.92 | PTGS1 (0.47) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL11283553 | 0.92 | PTGS1 (0.47) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL9827888 | 0.92 | PTGS1 (0.53) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL9623560 | 0.92 | PTGS1 (0.53) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL9361761 | 0.92 | PTGS1 (0.53) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL9827559 | 0.92 | PTGS1 (0.53) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL9361767 | 0.92 | PTGS1 (0.53) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL9623563 | 0.92 | PTGS1 (0.53) | PTGS1NR1I2HTR2CABCB11PDE4D | |
| SCHEMBL10834932 | 0.91 | PTGS1 (0.47) | PTGS1NR1I2HTR2CABCB11PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050267092-A1 | Novel cephalosporin compounds and process for preparing the same | LG LEF SCIENCES LTD. (KR) | 2005-12-01 | — | — | US | disclosed |
| US-4365062-A | BACTERICIDAL ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1982-12-21 | — | — | US | disclosed |
| US-4307116-A | BACTERICIDES | RHONE-POULENC INDUSTRIES (FR) | 1981-12-22 | — | — | US | disclosed |
| US-4307233-A | ANTIBACTERIAL AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1981-12-22 | — | — | US | disclosed |
| US-4307230-A | ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1981-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267092-A1 | Novel cephalosporin compounds and process for preparing the same | PEPD, CTRC, CHLSN | PTGS1 4041/4885NR1I2 1731/4885HTR2C 2321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.