Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18869583 | 0.78 | ESR1 (0.51) | ESR1DAOCNR1CNR2 | |
| SCHEMBL132181 | 0.76 | ESR1 (0.41) | ESR1DAORAF1 | |
| SCHEMBL280067 | 0.75 | ESR1 (0.40) | ESR1DAORAF1 | |
| SCHEMBL9148941 | 0.72 | ESR1 (0.37) | ESR1DAO | |
| SCHEMBL13551463 | 0.69 | ESR1 (0.41) | ESR1DAO | |
| SCHEMBL130154 | 0.69 | ESR1 (0.42) | ESR1DAO | |
| SCHEMBL7562787 | 0.68 | ESR1 (0.36) | ESR1DAORAF1 | |
| SCHEMBL1613336 | 0.68 | ESR1 (0.36) | ESR1DAO | |
| SCHEMBL16270669 | 0.67 | DAO (0.36) | ESR1DAORAF1 | |
| SCHEMBL129410 | 0.67 | MLYCD (0.41) | ESR1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599362-A | 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives | MITSUITOATSU CHEMICALS, INC. (JP) | 1986-07-08 | — | — | US | disclosed |
| US-4570005-A | REACTING THE ARYL PROPYL CHLORIDE WITH THE CORRESPONDING ARYL ALCOHOL OR ARYL MERCAPTAN | MITSUITOATSU CHEMICALS INC. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4397864-A | LOW TOXICITY | MITSUITOATSU CHEMICALS INC. (JP) | 1983-08-09 | — | — | US | disclosed |