Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10837667 | 0.91 | TACR1 (0.42) | TACR1TTRHTR2ASLC6A4ALOX5 | |
| SCHEMBL10837451 | 0.90 | TACR1 (0.37) | TACR1TTRPPARGFFAR1LPAR1 | |
| SCHEMBL10837306 | 0.89 | TACR1 (0.34) | TACR1TTRSLC6A4PPARGALOX5 | |
| SCHEMBL10838235 | 0.89 | TACR1 (0.48) | TACR1PPARGFFAR1MAOB | |
| SCHEMBL10836856 | 0.88 | TACR1 (0.36) | TACR1CHRM3KCNH2TTRHTR2A | |
| SCHEMBL9558257 | 0.87 | TACR1 (0.36) | TACR1KIF11TTRPPARGFFAR1 | |
| SCHEMBL10837586 | 0.87 | TACR1 (0.37) | TACR1TTRHTR2ASLC6A4PPARG | |
| SCHEMBL10837086 | 0.87 | L3MBTL1 (0.40) | TACR1ALOX5FFAR1 | |
| SCHEMBL10837407 | 0.86 | PPARG (0.35) | TACR1TTRPPARGFFAR1LPAR1 | |
| SCHEMBL10837117 | 0.86 | NPC1 (0.38) | TACR1CYP2C9TTRPPARGLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599362-A | 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives | MITSUITOATSU CHEMICALS, INC. (JP) | 1986-07-08 | — | — | US | disclosed |