Styrene

Styrene

SCHEMBL10837745

C=Cc1ccccc1.Cc1ccccc1C.Cc1ccccc1C.Cc1ccccc1C.Cc1ccccc1C

nearest known ligand 0.74

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.74
TSHR P16473 4/20 0.74
ACHE P22303 3/20 0.53
TDP1 Q9NUW8 2/20 0.50
TP53 P04637 1/20 0.50
HDAC8 Q9BY41 2/20 0.42
TTR P02766 1/20 0.40
ALOX5 P09917 1/20 0.40
PTGS1 P23219 1/20 0.40
PTGS2 P35354 1/20 0.40
MAOB P27338 1/20 0.38
CYP2A6 P11509 1/20 0.38
LMNA P02545 2/20 0.36
ALOX12 P18054 1/20 0.36
EGFR P00533 1/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL10458104 1.00 ALDH1A1 (0.74) ALDH1A1TSHRACHETDP1TP53
Styrene SCHEMBL1458566 1.00 ALDH1A1 (0.74) ALDH1A1TSHRACHETDP1TP53
Styrene SCHEMBL60600 1.00 ALDH1A1 (0.74) ALDH1A1TSHRACHETDP1TP53
Styrene SCHEMBL10386633 0.95 ALDH1A1 (0.67) ALDH1A1TSHRACHETDP1TP53
Styrene SCHEMBL7762250 0.93 TSHR (0.64) ALDH1A1TSHRACHETDP1TP53
Styrene SCHEMBL6848393 0.87 TSHR (0.56) ALDH1A1TSHRACHETDP1TP53
Styrene SCHEMBL8336803 0.86 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL7160606 0.86 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL4986035 0.86 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL9776790 0.86 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4624869-A Alkyd resin cure modifiers SCM CORPORATION (US) 1986-11-25 US disclosed