Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | HPGD | P15428 | 2/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 1/20 | 0.78 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | TOP2A | P11388 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.58 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884780 | 0.88 | KDM4E (0.61) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Enrofloxacin SCHEMBL28954444 | 0.88 | KDM4E (0.89) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Enrofloxacin SCHEMBL6742652 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Enrofloxacin SCHEMBL149150 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Enrofloxacin SCHEMBL17554684 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Enrofloxacin SCHEMBL29349852 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL5007468 | 0.87 | KDM4E (0.75) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL14010224 | 0.87 | KDM4E (0.78) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Enrofloxacin SCHEMBL10741694 | 0.87 | KDM4E (0.98) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Enrofloxacin SCHEMBL16784595 | 0.87 | KDM4E (0.98) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117474-B1 | QUINOLONE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1986-10-29 | — | — | EP | disclosed |
| EP-0118854-B1 | BACTERICIDAL AGENT CONTAINING QUINOLONE-CARBOXYLIC ACIDS | BAYER AG (DE) | 1986-07-23 | — | — | EP | disclosed |
| US-4563448-A | PHYTOPATHOGENS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| US-4559342-A | Quinolone acids and antibacterial agents containing these compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-17 | — | — | US | disclosed |
| EP-0118854-A1 | Bactericidal agent containing quinolone-carboxylic acids | BAYER AG (DE) | 1984-09-19 | — | — | EP | disclosed |