Enrofloxacin

Enrofloxacin

SCHEMBL149150

CCN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 1.00
ALDH1A1 P00352 4/20 1.00
LMNA P02545 3/20 1.00
HPGD P15428 2/20 1.00
HSD17B10 Q99714 2/20 1.00
MAPT P10636 1/20 1.00
TOP2B Q02880 2/20 0.73
CYP1A2 P05177 1/20 0.73
TOP2A P11388 1/20 0.73
CYP2C9 P11712 1/20 0.73
CA1 P00915 1/20 0.63
CA2 P00918 1/20 0.63
PIK3CG P48736 5/20 0.62
PIK3CD O00329 3/20 0.62
PIK3R1 P27986 3/20 0.62
PIK3CA P42336 3/20 0.62
DRD3 P35462 1/20 0.62
HRH3 Q9Y5N1 1/20 0.61
HTT P42858 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Enrofloxacin SCHEMBL29349852 1.00 KDM4E (1.00) KDM4EALDH1A1LMNAHPGDHSD17B10
Enrofloxacin SCHEMBL17554684 1.00 KDM4E (1.00) KDM4EALDH1A1LMNAHPGDHSD17B10
Enrofloxacin SCHEMBL6742652 1.00 KDM4E (1.00) KDM4EALDH1A1LMNAHPGDHSD17B10
Enrofloxacin SCHEMBL10741694 0.99 KDM4E (0.98) KDM4EALDH1A1LMNAHPGDHSD17B10
Enrofloxacin SCHEMBL17554678 0.99 KDM4E (0.98) KDM4EALDH1A1LMNAHPGDHSD17B10
Enrofloxacin SCHEMBL16784595 0.99 KDM4E (0.98) KDM4EALDH1A1LMNAHPGDHSD17B10
Enrofloxacin SCHEMBL9788077 0.99 KDM4E (0.98) KDM4EALDH1A1LMNAHPGDHSD17B10
Enrofloxacin SCHEMBL976909 0.99 KDM4E (0.98) KDM4EALDH1A1LMNAHPGDHSD17B10
Enrofloxacin SCHEMBL8027963 0.99 KDM4E (0.98) KDM4EALDH1A1LMNAHPGDHSD17B10
Enrofloxacin SCHEMBL29649713 0.99 KDM4E (0.98) KDM4EALDH1A1LMNAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15910 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117330561-B Method for colorimetric analysis of antibiotics by paper-based detection chip and application thereof HUNAN UNIVERSITY (CN) 2026-05-26 CN claimed
CN-122075390-A Preparation and application of novel cow uterus injectant 2026-05-26 CN claimed
WO-2026105158-A1 BIS(BENZYLISOQUINOLINE) ALKALOIDS AS TLR4 AGONIST TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) 2026-05-21 WO claimed
CN-119797565-B Method for rapidly removing enrofloxacin by cooperatively adding calcium peroxide through micro-nano aeration in aeration tank of three-tank two-dam of cultivation tail water treatment technology 中国水产科学研究院淡水渔业研究中心 2026-05-19 CN claimed
CN-118655129-B Method for detecting residual antibiotics in water body environment based on nano enzyme 河南农业大学 2026-05-15 CN claimed
CN-122032601-A Zn (zinc)5(OH)6(CO3)2/BiVO4Heterojunction photocatalyst and preparation method and application thereof 安徽大学 2026-05-15 CN claimed
CN-121286604-B Feed additive for regulating intestinal microecology to eliminate antibiotic residues 湖南坤源生物科技有限公司 2026-05-12 CN claimed
US-12624057-B2 Bisphosphonate quinolone conjugates and uses thereof BIOVINC, LLC (US) 2026-05-12 US claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
EP-0443381-A1 Effervescent composition, its production and use Takeda Chemical Industries, Ltd. (JP) 1991-08-28 EP claimed
US-5023257-A Related to ciprofloxacin, in the form of oily suspension; bacterial infections BAYER AKTIENGESELLSCHAFT (DE) 1991-06-11 US claimed
EP-0187315-B1 BASIC QUINOLONECARBOXYLIC-ACID PREPARATIONS BAYER AG (DE) 1991-04-17 EP claimed
EP-0359076-A2 pH-neutral aqueous solutions of quinolone-carboxylic acids BAYER AG (DE) 1990-03-21 EP claimed
US-4895803-A QUINOLINE-OR NAPHTHAPYRIDINE/1,8-/ DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1990-01-23 US claimed
US-4772605-A STORAGE STABILITY BAYER AKTIENGESELLSCHAFT (DE) 1988-09-20 US claimed
US-4670444-A 7-amino-1-cyclopropyl-4-oxo-1, 4-dihydro-quinoline-and naphthyridine-3-carboxylic acids and antibacterial agents containing these compounds BAYER AKTIENGESELLSCHAFT (DE) 1987-06-02 US claimed
EP-0078362-B1 1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-PIPERAZINO-QUINOLINE-3-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS CONTAINING THEM BAYER AG (DE) 1986-10-22 EP claimed
US-4563459-A FUNGICIDES AND BACTERICIDES FOR AGRICULTURAL USE BAYER AKTIENGESELLSCHAFT (DE) 1986-01-07 US claimed
EP-0078362-A2 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-quinoline-3-carboxylic acids, process for their preparation and antibacterial agents containing them BAYER AG (DE) 1983-05-11 EP claimed