Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839872 | 0.93 | MAPT (0.59) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL10840165 | 0.92 | MAPT (0.56) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL10840202 | 0.90 | MAPT (0.44) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| Quizalofop-P-Ethyl SCHEMBL53466 | 0.89 | MAPT (0.67) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| Quizalofop Ethyl Ester SCHEMBL9139248 | 0.89 | MAPT (0.67) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| Quizalofop-P-Ethyl SCHEMBL29474422 | 0.89 | MAPT (0.67) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| Quizalofop Ethyl Ester SCHEMBL30406 | 0.89 | MAPT (0.67) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| Quizalofop Ethyl Ester SCHEMBL23045020 | 0.88 | MAPT (0.66) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| Quizalofop-P-Ethyl SCHEMBL23045019 | 0.88 | MAPT (0.66) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL10973729 | 0.87 | MAPT (0.65) | MAPTLMNACYP1A2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4582526-A | Carbamic acid ester herbicides | HOFFMANN-LA ROCHE INC. (US) | 1986-04-15 | — | — | US | disclosed |