Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838995 | 0.93 | MAPT (0.45) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL10839016 | 0.90 | MAPT (0.57) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL8508358 | 0.89 | ALDH1A1 (0.51) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL10839775 | 0.88 | GAA (0.43) | MAPTCYP1A2CYP3A4TP53ALOX15 | |
| SCHEMBL10969382 | 0.85 | ALDH1A1 (0.48) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL10840123 | 0.85 | MAPT (0.46) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL733453 | 0.83 | MAPT (0.53) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL10881162 | 0.83 | ALDH1A1 (0.47) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL10967029 | 0.82 | ALDH1A1 (0.45) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL10839872 | 0.82 | MAPT (0.59) | MAPTLMNACYP1A2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4582526-A | Carbamic acid ester herbicides | HOFFMANN-LA ROCHE INC. (US) | 1986-04-15 | — | — | US | claimed |