Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | ESR1 | P03372 | 1/20 | 0.77 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.77 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.77 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.71 |
| ▸ | DRD2 | P14416 | 1/20 | 0.71 |
| ▸ | DRD3 | P35462 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839225 | 1.00 | MAPT (0.77) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL11802087 | 0.92 | ALDH1A1 (0.76) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL11231581 | 0.92 | ALDH1A1 (0.76) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL11154468 | 0.92 | ALDH1A1 (0.76) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL11154449 | 0.92 | ALDH1A1 (0.76) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL11055755 | 0.92 | ALDH1A1 (0.76) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL10811020 | 0.92 | ALDH1A1 (0.76) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL11045122 | 0.92 | ALDH1A1 (0.76) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| Water SCHEMBL11324180 | 0.91 | HSD17B10 (0.77) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| Hydrochloric Acid SCHEMBL10840101 | 0.91 | ALDH1A1 (0.75) | MAPTHSD17B10KMT2AMEN1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4579684-A | Process for the manufacture of enol derivatives | CIBA-GEIGY CORPORATION (US) | 1986-04-01 | — | — | US | disclosed |
| US-4550162-A | Process for the manufacture of enol derivatives | CIBA-GEIGY CORPORATION (US) | 1985-10-29 | — | — | US | disclosed |
| US-4434287-A | Cephalosporin derivatives | CIBA-GEIGY CORPORATION (US) | 1984-02-28 | — | — | US | disclosed |
| US-4405778-A | Process for preparing cephalosporin ethers | CIBA-GEIGY CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |
| US-4319027-A | Process for the manufacture of ceohem enol derivatives | CIBA-GEIGY CORPORATION (US) | 1982-03-09 | — | — | US | disclosed |
| US-4301278-A | BY HYDROGENATION IN THE PRESENCE OF A CATALYST | CIBA-GEIGY CORPORATION (US) | 1981-11-17 | — | — | US | disclosed |
| US-4293462-A | Process for the manufacture of enol derivatives, and intermediates | CIBA-GEIGY CORPORATION (US) | 1981-10-06 | — | — | US | disclosed |
| US-4255328-A | CEPHALOSPORINS | CIBA-GEIGY CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| US-4147864-A | Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |
| US-4110533-A | PROCESS FOR THE MANUFACTURE OF ENOL DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |