Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | RECQL | P46063 | 5/20 | 0.46 |
| ▸ | BLM | P54132 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | UCK2 | Q9BZX2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10818115 | 0.95 | MAPT (0.51) | MAPTTP53SMN1; SMN2TDP1POLB | |
| SCHEMBL10818213 | 0.92 | MEN1 (0.53) | MAPTTP53SMN1; SMN2TDP1POLB | |
| SCHEMBL10818216 | 0.91 | MAPT (0.50) | MAPTTP53SMN1; SMN2TDP1POLB | |
| SCHEMBL10817045 | 0.90 | MAPT (0.48) | MAPTTP53SMN1; SMN2TDP1POLB | |
| SCHEMBL10812773 | 0.82 | MAPT (0.55) | MAPTTP53SMN1; SMN2TDP1POLB | |
| SCHEMBL10816008 | 0.82 | MEN1 (0.45) | MAPTTP53SMN1; SMN2TDP1POLB | |
| SCHEMBL10839199 | 0.82 | MAPT (0.55) | MAPTTP53SMN1; SMN2TDP1POLB | |
| SCHEMBL10818493 | 0.82 | TP53 (0.56) | MAPTTP53SMN1; SMN2TDP1POLB | |
| SCHEMBL10817930 | 0.80 | TP53 (0.55) | MAPTTP53SMN1; SMN2TDP1POLB | |
| SCHEMBL10817642 | 0.80 | MAPT (0.55) | MAPTTP53SMN1; SMN2TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4578380-A | 5H-[1]benzopyrano[2,3-d]pyrimidine derivatives useful for controlling lesions of the gastric and duodenal mucous membranes | WARNER-LAMBERT COMPANY (US) | 1986-03-25 | — | — | US | disclosed |