Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 12/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27778757 | 0.97 | TSHR (0.47) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL3346971 | 0.94 | TSHR (0.50) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL1639544 | 0.94 | TSHR (0.50) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL5523111 | 0.94 | TSHR (0.40) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL8197016 | 0.91 | FDPS (0.39) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| Methylene Chloride SCHEMBL19064598 | 0.88 | TSHR (0.48) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| Methylene Chloride SCHEMBL2388456 | 0.88 | TSHR (0.48) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| Methylene Chloride SCHEMBL3865938 | 0.88 | TSHR (0.48) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| Methylene Chloride SCHEMBL2064725 | 0.88 | TSHR (0.48) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL8368835 | 0.88 | FDPS (0.37) | TSHRTHRBFDPSSMPD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4622380-A | Alkylidene bromo-substituted arylene acetal and/or ketal polymers | PPG INDUSTRIES, INC. (US) | 1986-11-11 | — | — | US | disclosed |