Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992053 | 1.00 | MAPT (0.47) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL10841031 | 0.97 | ALDH1A1 (0.47) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL10841038 | 0.97 | ALDH1A1 (0.47) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL10840007 | 0.92 | MAPT (0.45) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL10840004 | 0.92 | MAPT (0.45) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL11684462 | 0.91 | CTDSP1 (0.50) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL11726333 | 0.91 | CTDSP1 (0.50) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL10840431 | 0.91 | ALDH1A1 (0.43) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL10840439 | 0.91 | ALDH1A1 (0.43) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| SCHEMBL10548078 | 0.90 | CTDSP1 (0.48) | MAPTHSD17B10KMT2AMEN1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4579684-A | Process for the manufacture of enol derivatives | CIBA-GEIGY CORPORATION (US) | 1986-04-01 | — | — | US | disclosed |
| US-4550162-A | Process for the manufacture of enol derivatives | CIBA-GEIGY CORPORATION (US) | 1985-10-29 | — | — | US | disclosed |
| US-4434287-A | Cephalosporin derivatives | CIBA-GEIGY CORPORATION (US) | 1984-02-28 | — | — | US | disclosed |
| US-4319027-A | Process for the manufacture of ceohem enol derivatives | CIBA-GEIGY CORPORATION (US) | 1982-03-09 | — | — | US | disclosed |
| US-4293462-A | Process for the manufacture of enol derivatives, and intermediates | CIBA-GEIGY CORPORATION (US) | 1981-10-06 | — | — | US | disclosed |
| US-4110533-A | PROCESS FOR THE MANUFACTURE OF ENOL DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |