Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | HTT | P42858 | 4/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 3/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 3/20 | 1.00 |
| ▸ | RELA | Q04206 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 2/20 | 1.00 |
| ▸ | MPI | P34949 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.73 |
| ▸ | TP53 | P04637 | 6/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.73 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839114 | 0.89 | MAPT (0.80) | MAPTLMNASMN1; SMN2HTTNFKB1 | |
| SCHEMBL27253781 | 0.84 | MAPT (1.00) | MAPTLMNASMN1; SMN2HTTNFKB1 | |
| SCHEMBL27256997 | 0.84 | MAPT (0.79) | MAPTLMNASMN1; SMN2HTTNFKB1 | |
| SCHEMBL27253885 | 0.83 | MAPT (0.71) | MAPTLMNASMN1; SMN2HTTNFKB1 | |
| SCHEMBL2518179 | 0.83 | KDM4E (0.86) | MAPTLMNASMN1; SMN2HTTNFKB1 | |
| SCHEMBL27254151 | 0.82 | MAPT (0.75) | MAPTLMNASMN1; SMN2HTTNFKB1 | |
| Hydrochloric Acid SCHEMBL5594620 | 0.82 | KDM4E (0.83) | MAPTLMNASMN1; SMN2HTTNFKB1 | |
| SCHEMBL27253985 | 0.81 | MAPT (0.68) | MAPTLMNASMN1; SMN2HTTNFKB1 | |
| SCHEMBL13310327 | 0.80 | KDM4E (0.76) | MAPTLMNASMN1; SMN2HTTNFKB1 | |
| SCHEMBL10507781 | 0.80 | MAPT (0.67) | MAPTLMNASMN1; SMN2HTTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092083-A1 | SMALL MOLECULAR WEIGHT CHEMICAL COMPOUND TO ANTAGONIZE EPH-EPHRIN TETRAMERIZATION AND INHIBIT BIDIRECTIONAL SIGNALING | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-05-02 | — | — | WO | disclosed |
| US-4629728-A | ANTIISCHEMIC AND -METABOLIC AGENTS | ADIR S.A.R.L. (FR) | 1986-12-16 | — | — | US | disclosed |