Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.70 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | HTT | P42858 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.70 |
| ▸ | RELA | Q04206 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | MPI | P34949 | 2/20 | 0.70 |
| ▸ | APP | P05067 | 2/20 | 0.66 |
| ▸ | DRD4 | P21917 | 2/20 | 0.64 |
| ▸ | DRD3 | P35462 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 5/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839910 | 0.89 | DRD2 (0.65) | MAPTKDM4EKMT2ANPSR1ALOX12 | |
| SCHEMBL27253836 | 0.85 | KDM4E (0.80) | MAPTKDM4EKMT2ANPSR1ALOX12 | |
| SCHEMBL27253809 | 0.85 | KDM4E (0.80) | MAPTKDM4EKMT2ANPSR1ALOX12 | |
| SCHEMBL2518179 | 0.83 | KDM4E (0.86) | MAPTKDM4EKMT2ANPSR1ALOX12 | |
| SCHEMBL10839892 | 0.82 | MAPT (1.00) | MAPTKDM4EKMT2ANPSR1ALOX12 | |
| SCHEMBL27253895 | 0.82 | KDM4E (0.75) | MAPTKDM4EKMT2ANPSR1ALOX12 | |
| Hydrochloric Acid SCHEMBL5594620 | 0.82 | KDM4E (0.83) | MAPTKDM4EKMT2ANPSR1ALOX12 | |
| SCHEMBL27253843 | 0.81 | KDM4E (0.69) | MAPTKDM4EKMT2ANPSR1ALOX12 | |
| SCHEMBL13310328 | 0.80 | KDM4E (0.75) | MAPTKDM4EKMT2ANPSR1ALOX12 | |
| SCHEMBL5595007 | 0.80 | KDM4E (0.78) | MAPTKDM4EKMT2ANPSR1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092083-A1 | SMALL MOLECULAR WEIGHT CHEMICAL COMPOUND TO ANTAGONIZE EPH-EPHRIN TETRAMERIZATION AND INHIBIT BIDIRECTIONAL SIGNALING | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-05-02 | — | — | WO | disclosed |