Acrylic Acid

Acrylic Acid

SCHEMBL10840397

C=C(C)C(=O)OCCOCC.C=CC(=O)O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.79
TSHR P16473 8/20 0.50
ALDH1A1 P00352 7/20 0.50
TP53 P04637 2/20 0.41
HIF1A Q16665 2/20 0.41
HSD17B10 Q99714 2/20 0.41
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
ALOX15 P16050 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
GLO1 Q04760 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL8837559 0.91 THRB (0.63) THRBTSHRALDH1A1TP53HIF1A
Acetic Acid SCHEMBL27984547 0.89 THRB (0.92) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL36524 0.89 THRB (1.00) THRBTSHRALDH1A1TP53HIF1A
Acrylic Acid SCHEMBL2693137 0.89 THRB (0.59) THRBTSHRALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL8041672 0.87 THRB (0.89) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL8850759 0.87 THRB (0.96) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL8850621 0.87 THRB (0.96) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL209194 0.87 THRB (0.96) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL16504107 0.87 THRB (0.96) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL11754913 0.87 THRB (0.96) THRBTSHRALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105120956-B The pharmaceutical preparation of anti-distort 普渡制药公司 2019-03-08 CN disclosed
US-4612209-A PHOTOPOLYMERIZABLE ACRYLIC ACIDS OR ESTERS AND EPOXYIDE RESIN CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed