Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23124039 | 0.87 | AR (0.44) | ARDRD2DRD3PNMTPGR | |
| SCHEMBL29789835 | 0.87 | AR (0.44) | ARDRD2DRD3PNMTPGR | |
| SCHEMBL5651931 | 0.76 | AR (0.46) | ARPGRNR3C2 | |
| SCHEMBL10841146 | 0.75 | AR (0.47) | ARPGRNR3C2 | |
| SCHEMBL5328438 | 0.75 | AR (0.47) | ARPNMTPGRKDM1ANR3C2 | |
| SCHEMBL10840954 | 0.75 | AR (0.48) | ARPGRNR3C2 | |
| SCHEMBL6986056 | 0.72 | PDE3B (0.46) | AR | |
| SCHEMBL288540 | 0.72 | DRD2 (0.55) | DRD2DRD3PNMTPSEN1PSEN2 | |
| SCHEMBL10840081 | 0.71 | MAPT (0.52) | ARPNMTPGRNR3C2 | |
| SCHEMBL15964812 | 0.71 | MAPT (0.53) | DRD2DRD3PNMTPGRKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |