Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 14/20 | 0.41 |
| ▸ | HTR2A | P28223 | 11/20 | 0.41 |
| ▸ | HTR2B | P41595 | 9/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19656991 | 0.82 | HTR2C (0.45) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL11478309 | 0.75 | HTR2A (0.31) | HTR2CHTR2AHTR2B | |
| SCHEMBL20910806 | 0.74 | MEN1 (0.33) | — | |
| SCHEMBL31607531 | 0.73 | MEN1 (0.54) | HTR2C | |
| SCHEMBL20910643 | 0.73 | MEN1 (0.54) | HTR2CHTR2AHTR2B | |
| SCHEMBL19657057 | 0.73 | MEN1 (0.54) | HTR2C | |
| SCHEMBL10840512 | 0.71 | HTR2C (0.45) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL10840681 | 0.71 | MEN1 (0.38) | HTR2CHTR2AHTR2B | |
| SCHEMBL9828466 | 0.69 | HTR2C (0.46) | HTR2CSLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL10839305 | 0.69 | PGR (0.43) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |