SCHEMBL10841925

SCHEMBL10841925

CCCCOc1ccc[c]c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
MCHR1 Q99705 2/20 0.41
CYP19A1 P11511 1/20 0.40
LTA4H P09960 2/20 0.39
TP53 P04637 2/20 0.39
GAA P10253 2/20 0.39
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 2/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38
NR1I2 O75469 1/20 0.38
CHRM2 P08172 1/20 0.38
CYP3A4 P08684 1/20 0.38
ADRA2A P08913 1/20 0.38
OPRK1 P41145 1/20 0.38
HTR2B P41595 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10515437 0.91 HTR2C (0.40) CYP1A2CYP2C9CYP2C19MCHR1TP53
SCHEMBL20836406 0.84 SMN1; SMN2 (0.40) CYP1A2CYP2C9CYP2C19GAAKMT2A
SCHEMBL2778847 0.82 ALDH1A1 (0.45) CYP1A2CYP2C19GAAHTTKMT2A
SCHEMBL677482 0.81 CYP1A2 (0.50) CYP1A2CYP2C9CYP2C19MCHR1CYP19A1
SCHEMBL17046261 0.81 TSHR (0.38) GAATSHRHTTLMNAMAPT
SCHEMBL1225445 0.81 IDO1 (0.40) TP53GAATSHRHTTLMNA
SCHEMBL2971838 0.80 CYP1A2 (0.49) CYP1A2CYP2C9CYP2C19MCHR1CYP19A1
SCHEMBL2961113 0.80 CYP1A2 (0.49) CYP1A2CYP2C9CYP2C19MCHR1CYP19A1
SCHEMBL9088864 0.80 CYP1A2 (0.49) CYP1A2CYP2C9CYP2C19MCHR1CYP19A1
SCHEMBL921028 0.80 CYP1A2 (0.49) CYP1A2CYP2C9CYP2C19MCHR1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100564383-C Organosilicon compound and manufacture method thereof SUMITOMO CHEMICAL CO (JP) 2009-12-02 CN disclosed
CN-1930174-A Organosilicon compound and method for producing same SUMITOMO CHEMICAL CO (JP) 2007-03-14 CN disclosed
EP-0189774-A1 Process for production of N,N-disubstituted carboxylic acid amides TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-08-06 EP disclosed