Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | DHODH | Q02127 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841511 | 0.94 | DHODH (0.57) | MAPTNPSR1L3MBTL1KDM4EMAPK1 | |
| SCHEMBL10841732 | 0.93 | DHODH (0.54) | MAPTNPSR1L3MBTL1KDM4EMAPK1 | |
| SCHEMBL10840956 | 0.90 | NPSR1 (0.49) | MAPTNPSR1L3MBTL1KDM4EMAPK1 | |
| SCHEMBL10841764 | 0.90 | KDM4E (0.55) | MAPTNPSR1L3MBTL1KDM4EMAPK1 | |
| SCHEMBL10842906 | 0.89 | MAPT (0.51) | MAPTNPSR1L3MBTL1KDM4EMAPK1 | |
| SCHEMBL10861116 | 0.73 | DHODH (0.78) | MAPTNPSR1L3MBTL1KDM4EMAPK1 | |
| SCHEMBL395324 | 0.70 | DHODH (0.77) | MAPTNPSR1L3MBTL1KDM4EMAPK1 | |
| SCHEMBL10518687 | 0.70 | DHODH (0.68) | MAPTNPSR1L3MBTL1KDM4EMAPK1 | |
| SCHEMBL10861496 | 0.69 | DHODH (0.70) | MAPTNPSR1L3MBTL1KDM4EMAPK1 | |
| SCHEMBL10863692 | 0.69 | DHODH (0.90) | MAPTNPSR1L3MBTL1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | claimed |
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |