Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | DHODH | Q02127 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841732 | 0.92 | DHODH (0.54) | NPSR1MAPTKDM4EL3MBTL1MAPK1 | |
| SCHEMBL10842149 | 0.90 | MAPT (0.56) | NPSR1MAPTKDM4EL3MBTL1MAPK1 | |
| SCHEMBL10842906 | 0.89 | MAPT (0.51) | NPSR1MAPTKDM4EL3MBTL1MAPK1 | |
| SCHEMBL10841511 | 0.87 | DHODH (0.57) | NPSR1MAPTKDM4EL3MBTL1MAPK1 | |
| SCHEMBL10841764 | 0.85 | KDM4E (0.55) | NPSR1MAPTKDM4EL3MBTL1MAPK1 | |
| SCHEMBL10842071 | 0.82 | CHEK1 (0.37) | NPSR1MAPTKDM4EHPGDDHODH | |
| SCHEMBL10842773 | 0.75 | KDM4E (0.47) | NPSR1MAPTKDM4EL3MBTL1MAPK1 | |
| SCHEMBL545096 | 0.74 | DHODH (0.75) | NPSR1MAPTKDM4EL3MBTL1MAPK1 | |
| SCHEMBL10842915 | 0.72 | CHEK1 (0.45) | NPSR1MAPTKDM4EMAPK1HPGD | |
| SCHEMBL7068076 | 0.69 | DHODH (0.65) | NPSR1MAPTKDM4EHPGDDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |