Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 5/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845047 | 0.81 | FFAR1 (0.37) | FFAR1ESR1ESR2NPC1RAB9A | |
| SCHEMBL10644924 | 0.80 | ESR1 (0.39) | ESR1ESR2NPC1RAB9AGPBAR1 | |
| SCHEMBL10642245 | 0.79 | ESR1 (0.37) | MMP2ESR1ESR2NPC1RAB9A | |
| SCHEMBL10642051 | 0.78 | ESR1 (0.44) | FFAR1MMP2MMP7MMP14ESR1 | |
| SCHEMBL10644787 | 0.76 | ESR1 (0.40) | ESR1ESR2NPC1RAB9AGPBAR1 | |
| SCHEMBL11558270 | 0.76 | ESR1 (0.48) | ESR1ESR2NPC1RAB9A | |
| SCHEMBL10661416 | 0.75 | ALDH1A1 (0.50) | ESR1ESR2 | |
| SCHEMBL10644719 | 0.75 | PTGS1 (0.39) | FFAR1MMP2MMP7MMP14NPC1 | |
| SCHEMBL10661793 | 0.73 | ESR1 (0.72) | ESR1ESR2 | |
| SCHEMBL10645089 | 0.70 | ESR1 (0.39) | ESR1ESR2NPC1RAB9AGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4602028-A | Antihypertensive 3-aryl-1,2-benzisoxazol-sulfonyl and sulfinylalkanoic acids | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1986-07-22 | — | — | US | claimed |
| US-4602028-A | Antihypertensive 3-aryl-1,2-benzisoxazol-sulfonyl and sulfinylalkanoic acids | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1986-07-22 | — | — | US | disclosed |