Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845938 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTL3MBTL1PRSS1RAB9A | |
| SCHEMBL10843690 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTL3MBTL1PRSS1RAB9A | |
| SCHEMBL10845728 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTL3MBTL1PRSS1RAB9A | |
| SCHEMBL10842000 | 0.99 | ALDH1A1 (0.41) | ALDH1A1MAPTL3MBTL1PRSS1RAB9A | |
| SCHEMBL10842132 | 0.96 | MAPT (0.41) | ALDH1A1MAPTL3MBTL1PRSS1RAB9A | |
| SCHEMBL10841952 | 0.93 | ALDH1A1 (0.40) | ALDH1A1MAPTRAB9AHTTHPGD | |
| SCHEMBL10845298 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1PRSS1HTT | |
| SCHEMBL10844952 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1PRSS1HTT | |
| SCHEMBL10846006 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1PRSS1HTT | |
| SCHEMBL10844220 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1PRSS1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593029-A | Enzyme inhibitor | SYNTEX (U.S.A.) INC. (US) | 1986-06-03 | — | — | US | disclosed |