Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845148 | 1.00 | TBXAS1 (0.69) | TBXAS1CYP1A2USP2LMNAMEN1 | |
| SCHEMBL8306731 | 0.88 | TBXAS1 (0.55) | TBXAS1CYP1A2USP2LMNAMEN1 | |
| SCHEMBL8306732 | 0.88 | TBXAS1 (0.55) | TBXAS1CYP1A2USP2LMNAMEN1 | |
| SCHEMBL8306728 | 0.88 | TBXAS1 (0.55) | TBXAS1CYP1A2USP2LMNAMEN1 | |
| SCHEMBL11107726 | 0.88 | TBXAS1 (0.72) | TBXAS1CYP1A2USP2LMNAMEN1 | |
| SCHEMBL11107722 | 0.88 | TBXAS1 (0.72) | TBXAS1CYP1A2USP2LMNAMEN1 | |
| SCHEMBL28052073 | 0.86 | TBXAS1 (0.70) | TBXAS1CYP1A2USP2LMNAMEN1 | |
| SCHEMBL11479922 | 0.86 | TBXAS1 (0.71) | TBXAS1CYP1A2USP2LMNAMEN1 | |
| SCHEMBL11479926 | 0.86 | TBXAS1 (0.71) | TBXAS1CYP1A2USP2LMNAMEN1 | |
| Ozagrel SCHEMBL27930741 | 0.85 | TBXAS1 (0.76) | TBXAS1CYP1A2USP2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005563-A | N-benzyl imidazole derivative and preparation method and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |
| US-4607046-A | THROMBOXANE SYNTHETASE INHIBITOR | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1986-08-19 | — | — | US | disclosed |
| EP-0058079-B1 | 4-(1-IMIDAZOLYLMETHYL)CINNAMIC ACID HYDROCHLORIDE MONOHYDRATE, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Kissei Pharmaceutical Co. Ltd. (JP) | 1985-01-23 | — | — | EP | disclosed |
| US-4226878-A | ANTIINFLAMMATORY, HYPOTENSIVES, ANTIHISTAMINES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1980-10-07 | — | — | US | disclosed |