Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 5/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.61 |
| ▸ | JUN | P05412 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | GUSB | P08236 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845639 | 1.00 | IAPP (0.76) | IAPPMAPTLMNANFKB1NFE2L2 | |
| SCHEMBL16576811 | 0.89 | NFKB1 (0.70) | IAPPMAPTLMNANFKB1NFE2L2 | |
| SCHEMBL10847763 | 0.87 | IAPP (0.75) | IAPPMAPTLMNANFKB1NFE2L2 | |
| SCHEMBL10847770 | 0.87 | IAPP (0.75) | IAPPMAPTLMNANFKB1NFE2L2 | |
| SCHEMBL3508745 | 0.85 | NFKB1 (0.70) | IAPPMAPTLMNANFKB1NFE2L2 | |
| SCHEMBL3508748 | 0.85 | NFKB1 (0.70) | IAPPMAPTLMNANFKB1NFE2L2 | |
| SCHEMBL2437376 | 0.84 | IAPP (0.64) | IAPPMAPTLMNANFKB1NFE2L2 | |
| SCHEMBL2437375 | 0.84 | IAPP (0.64) | IAPPMAPTLMNANFKB1NFE2L2 | |
| SCHEMBL2473767 | 0.84 | IAPP (0.64) | IAPPMAPTLMNANFKB1NFE2L2 | |
| SCHEMBL2441185 | 0.84 | IAPP (0.64) | IAPPMAPTLMNANFKB1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4611070-A | DYE-FORMING COMPONENTS FOR PRESSURE-SENSITIVE RECORDING OR COPYING | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-09 | — | — | US | disclosed |
| EP-0010740-B1 | SPIRODIPYRANES AND THEIR USE AS COLOUR FORMERS IN COPYING PROCESSES | BASF Aktiengesellschaft (DE) | 1982-04-21 | — | — | EP | disclosed |
| EP-0010740-A1 | Spirodipyranes and their use as colour formers in copying processes | BASF Aktiengesellschaft (DE) | 1980-05-14 | — | — | EP | disclosed |