Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.72 |
| ▸ | HTR7 | P34969 | 2/20 | 0.72 |
| ▸ | DRD2 | P14416 | 4/20 | 0.62 |
| ▸ | HTR2A | P28223 | 4/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | HTR6 | P50406 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6105283 | 0.90 | HTR1A (0.70) | HTR1AHTR7DRD2HTR2AKCNH2 | |
| SCHEMBL6104289 | 0.87 | HTR1A (0.69) | HTR1AHTR7DRD2HTR2AKCNH2 | |
| SCHEMBL10842323 | 0.86 | HTR1A (0.61) | HTR1AHTR7DRD2HTR2ADRD3 | |
| SCHEMBL6108056 | 0.85 | HTR1A (0.61) | HTR1AHTR7DRD2HTR2AKCNH2 | |
| SCHEMBL6105280 | 0.85 | HTR1A (0.64) | HTR1AHTR7DRD2HTR2AKCNH2 | |
| SCHEMBL6104704 | 0.85 | HTR1A (0.64) | HTR1AHTR7DRD2HTR2AKCNH2 | |
| SCHEMBL11634905 | 0.85 | HTR1A (0.64) | HTR1AHTR7DRD2HTR2ADRD3 | |
| SCHEMBL6105749 | 0.84 | HTR1A (0.60) | HTR1AHTR7DRD2HTR2AKCNH2 | |
| SCHEMBL6108140 | 0.84 | HTR1A (0.57) | HTR1AHTR7DRD2HTR2AKCNH2 | |
| SCHEMBL6108853 | 0.84 | HTR1A (0.66) | HTR1AHTR7DRD2HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590196-A | NON-OPIATE | BRISTOL-MYERS COMPANY (US) | 1986-05-20 | — | — | US | claimed |