Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.71 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.71 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.69 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.65 |
| ▸ | PPARG | P37231 | 7/20 | 0.65 |
| ▸ | PPARD | Q03181 | 7/20 | 0.65 |
| ▸ | PPARA | Q07869 | 7/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.65 |
| ▸ | TLR2 | O60603 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | FABP4 | P15090 | 2/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.65 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711608 | 1.00 | S1PR1 (0.71) | S1PR1S1PR3S1PR2ALDH1A1MAPT | |
| SCHEMBL8087476 | 1.00 | S1PR1 (0.71) | S1PR1S1PR3S1PR2ALDH1A1MAPT | |
| SCHEMBL11838563 | 1.00 | S1PR1 (0.71) | S1PR1S1PR3S1PR2ALDH1A1MAPT | |
| SCHEMBL11849076 | 1.00 | S1PR1 (0.71) | S1PR1S1PR3S1PR2ALDH1A1MAPT | |
| SCHEMBL25170021 | 1.00 | S1PR1 (0.71) | S1PR1S1PR3S1PR2ALDH1A1MAPT | |
| SCHEMBL25167617 | 1.00 | S1PR1 (0.71) | S1PR1S1PR3S1PR2ALDH1A1MAPT | |
| SCHEMBL879250 | 1.00 | S1PR1 (0.71) | S1PR1S1PR3S1PR2ALDH1A1MAPT | |
| SCHEMBL17693416 | 0.98 | ALDH1A1 (0.72) | S1PR1S1PR3S1PR2ALDH1A1MAPT | |
| SCHEMBL6151349 | 0.96 | S1PR1 (0.71) | S1PR1S1PR3S1PR2ALDH1A1MAPT | |
| SCHEMBL25173315 | 0.96 | MAPT (0.69) | S1PR1S1PR3S1PR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4609744-A | 4-oxo-benzopyran carboxylic acids | MERCK FROSST CANADA INC. (CA) | 1986-09-02 | — | — | US | disclosed |