Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10846610 | 0.91 | NOTUM (0.45) | NOTUMGRM5GRM1NOS3NOS2 | |
| SCHEMBL10846040 | 0.77 | BCHE (0.37) | NOTUMGRM5GRM1NOS3NOS2 | |
| SCHEMBL10846409 | 0.74 | PDCD1 (0.34) | NOTUMGRM5GRM1NOS3NOS2 | |
| SCHEMBL4825821 | 0.74 | NOTUM (0.49) | NOTUMDRD2TRPA1PNMTESR2 | |
| SCHEMBL14053099 | 0.74 | NOTUM (0.36) | NOTUMTRPA1ESR2 | |
| SCHEMBL10846178 | 0.73 | NOTUM (0.43) | NOTUMTRPA1 | |
| SCHEMBL5109816 | 0.71 | CES1 (0.46) | NOTUMNOS3NOS2DRD2ADRA2A | |
| SCHEMBL30173200 | 0.70 | NOTUM (0.44) | NOTUMDRD2TRPA1PNMTADRA2A | |
| SCHEMBL20597517 | 0.70 | NOTUM (1.00) | NOTUM | |
| SCHEMBL20597290 | 0.69 | NOTUM (0.79) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605748-A | INSECTICIDES, MITICIDES | FMC CORPORATION (US) | 1986-08-12 | — | — | US | claimed |
| US-4605748-A | INSECTICIDES, MITICIDES | FMC CORPORATION (US) | 1986-08-12 | — | — | US | disclosed |
| US-4487778-A | Insecticidal esters derived from benzocycloalkane-thiophenemethyl compounds | FMC CORPORATION (US) | 1984-12-11 | — | — | US | disclosed |