Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 2/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10846054 | 0.91 | CHRNE (0.34) | PDCD1CD274NOS3NOS2PGR | |
| SCHEMBL10846040 | 0.77 | BCHE (0.37) | NOS3NOS2NOTUMALDH1A1GRM5 | |
| SCHEMBL10846178 | 0.76 | NOTUM (0.43) | NOTUMALDH1A1 | |
| SCHEMBL11000829 | 0.76 | PNMT (0.47) | PDCD1CD274PGRALDH1A1 | |
| SCHEMBL10844643 | 0.75 | NOS3 (0.32) | NOS3NOS2ALDH1A1ADRA2AADRA2B | |
| SCHEMBL10846830 | 0.75 | ALDH1A1 (0.31) | ALDH1A1GAA | |
| SCHEMBL10845839 | 0.74 | NOTUM (0.53) | NOS3NOS2NOTUMGRM5GRM1 | |
| SCHEMBL5109816 | 0.71 | CES1 (0.46) | NOS3NOS2NOTUMALDH1A1GAA | |
| SCHEMBL20656177 | 0.70 | CYP2A6 (0.39) | PDCD1CD274ALDH1A1PTGS1ADRA2A | |
| SCHEMBL10847041 | 0.68 | HSP90AA1 (0.40) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605748-A | INSECTICIDES, MITICIDES | FMC CORPORATION (US) | 1986-08-12 | — | — | US | claimed |
| US-4605748-A | INSECTICIDES, MITICIDES | FMC CORPORATION (US) | 1986-08-12 | — | — | US | disclosed |
| US-4487778-A | Insecticidal esters derived from benzocycloalkane-thiophenemethyl compounds | FMC CORPORATION (US) | 1984-12-11 | — | — | US | disclosed |