Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 6/20 | 1.00 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 1.00 |
| ▸ | CHKA | P35790 | 2/20 | 0.59 |
| ▸ | INSR | P06213 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18989408 | 1.00 | KDM4A (1.00) | KDM4AKDM2ACHKAINSRMEN1 | |
| SCHEMBL13924756 | 1.00 | KDM4A (1.00) | KDM4AKDM2ACHKAINSRMEN1 | |
| SCHEMBL18989411 | 1.00 | KDM4A (1.00) | KDM4AKDM2ACHKAINSRMEN1 | |
| SCHEMBL10846148 | 1.00 | KDM4A (1.00) | KDM4AKDM2ACHKAINSRMEN1 | |
| SCHEMBL10846534 | 1.00 | KDM4A (1.00) | KDM4AKDM2ACHKAINSRMEN1 | |
| SCHEMBL10844380 | 1.00 | KDM4A (1.00) | KDM4AKDM2ACHKAINSRMEN1 | |
| SCHEMBL10844383 | 1.00 | KDM4A (1.00) | KDM4AKDM2ACHKAINSRMEN1 | |
| SCHEMBL13417473 | 1.00 | KDM4A (1.00) | KDM4AKDM2ACHKAINSRMEN1 | |
| SCHEMBL21300082 | 1.00 | KDM4A (1.00) | KDM4AKDM2ACHKAINSRMEN1 | |
| SCHEMBL10845910 | 1.00 | KDM4A (1.00) | KDM4AKDM2ACHKAINSRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0139440-A2 | Pyridinium compounds | JOHN WYETH & BROTHER LIMITED (GB) | 1985-05-02 | — | — | EP | claimed |
| US-4608379-A | TOPICAL ADMINISTERING | JOHN WYETH & BROTHER LIMITED (GB) | 1986-08-26 | — | — | US | disclosed |
| EP-0139440-A2 | Pyridinium compounds | JOHN WYETH & BROTHER LIMITED (GB) | 1985-05-02 | — | — | EP | disclosed |