SCHEMBL18989408

SCHEMBL18989408

CCCCCCCCCCCCCCCC[n+]1ccc(/C=C/c2ccc(N(C)C)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4A O75164 6/20 1.00
▸ KDM2A Q9Y2K7 6/20 1.00
▸ CHKA P35790 2/20 0.59
▸ INSR P06213 3/20 0.58
▸ MEN1 O00255 4/20 0.54
▸ MAPT P10636 4/20 0.54
▸ KMT2A Q03164 4/20 0.54
▸ HTT P42858 4/20 0.54
▸ SMN1; SMN2 Q16637 3/20 0.54
▸ NPSR1 Q6W5P4 2/20 0.54
▸ LMNA P02545 2/20 0.54
▸ GAA P10253 1/20 0.54
▸ CASP1 P29466 1/20 0.54
▸ BRCA1 P38398 1/20 0.54
▸ CASP7 P55210 1/20 0.54
▸ HBB P68871 1/20 0.54
▸ ALDH1A1 P00352 1/20 0.54
▸ ALPG P10696 1/20 0.54
▸ THRB P10828 1/20 0.54
▸ GFER P55789 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10846534 1.00 KDM4A (1.00) KDM4AKDM2ACHKAINSRMEN1
SCHEMBL13924756 1.00 KDM4A (1.00) KDM4AKDM2ACHKAINSRMEN1
SCHEMBL10844380 1.00 KDM4A (1.00) KDM4AKDM2ACHKAINSRMEN1
SCHEMBL10845909 1.00 KDM4A (1.00) KDM4AKDM2ACHKAINSRMEN1
SCHEMBL10846148 1.00 KDM4A (1.00) KDM4AKDM2ACHKAINSRMEN1
SCHEMBL13417473 1.00 KDM4A (1.00) KDM4AKDM2ACHKAINSRMEN1
SCHEMBL10844383 1.00 KDM4A (1.00) KDM4AKDM2ACHKAINSRMEN1
SCHEMBL18989411 1.00 KDM4A (1.00) KDM4AKDM2ACHKAINSRMEN1
SCHEMBL21300082 1.00 KDM4A (1.00) KDM4AKDM2ACHKAINSRMEN1
SCHEMBL10845910 1.00 KDM4A (1.00) KDM4AKDM2ACHKAINSRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180364245-A1 Polymeric Dye Ratiometric Sensor for Analyte Detection and Methods of Using the Same BECTON, DICKINSON AND COMPANY 2018-12-20 — — US disclosed
WO-2017105927-A1 POLYMERIC DYE RATIOMETRIC SENSOR FOR ANALYTE DETECTION AND METHODS OF USING THE SAME BECTON, DICKINSON AND COMPANY (US) 2017-06-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180364245-A1 Polymeric Dye Ratiometric Sensor for Analyte Detection and Methods of Using the Same PGLS, SPR, DDOST KDM4A 4147/4885KDM2A 4233/4885CHKA 3458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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