Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | LEF1 | Q9UJU2 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10846580 | 1.00 | ABCB1 (0.32) | ABCB1PI4KBSCN9ALEF1GSK3B | |
| SCHEMBL9481102 | 0.87 | GAA (0.41) | PI4KBSCN9ALEF1GSK3BDYRK1A | |
| SCHEMBL9481109 | 0.87 | GAA (0.41) | PI4KBSCN9ALEF1GSK3BDYRK1A | |
| SCHEMBL9482908 | 0.87 | GAA (0.41) | PI4KBSCN9ALEF1GSK3BDYRK1A | |
| SCHEMBL9481637 | 0.79 | GSK3B (0.37) | PI4KBSCN9AGSK3BDYRK1ALCK | |
| SCHEMBL26678642 | 0.79 | PI4KB (0.38) | PI4KBSCN9AGSK3BDYRK1ALCK | |
| SCHEMBL8983013 | 0.71 | GAA (0.45) | ABCB1PI4KBLCKGAALMNA | |
| SCHEMBL8983007 | 0.71 | GAA (0.45) | ABCB1PI4KBLCKGAALMNA | |
| SCHEMBL14885115 | 0.71 | GAA (0.45) | ABCB1PI4KBLCKGAALMNA | |
| SCHEMBL21705628 | 0.70 | LCK (0.41) | PI4KBSCN9AGSK3BDYRK1ALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616081-A | ANTIBIOTIC, BACTERICIDE WITH GOOD ABSORTION AND STABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0098609-A2 | Novel cephalosporin compounds | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-01-18 | — | — | EP | disclosed |