Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 5/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600848 | 0.84 | PI4KB (0.42) | LCKPI4KBCA1CA2GSK3B | |
| SCHEMBL20557380 | 0.83 | PI4KB (0.39) | LCKPI4KBCA1CA2GSK3B | |
| SCHEMBL26678642 | 0.81 | PI4KB (0.38) | LCKPI4KBCA1CA2GSK3B | |
| SCHEMBL22031128 | 0.80 | CA1 (0.39) | LCKPI4KBCA1CA2GSK3B | |
| SCHEMBL22031127 | 0.80 | CDK5 (0.44) | LCKPI4KBCA1CA2GSK3B | |
| SCHEMBL24044235 | 0.80 | CDK5 (0.44) | LCKPI4KBCA1CA2GSK3B | |
| SCHEMBL28935820 | 0.80 | GSK3B (0.38) | LCKPI4KBCA1CA2GSK3B | |
| SCHEMBL28935615 | 0.80 | PI4KB (0.37) | LCKPI4KBCA1CA2GSK3B | |
| SCHEMBL9481637 | 0.79 | GSK3B (0.37) | LCKPI4KBCA1CA2GSK3B | |
| SCHEMBL1796358 | 0.79 | ABCB1 (0.38) | LCKPI4KBCA1CA2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743081-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | Pretzel Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| EP-4041730-B1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2026-05-13 | — | — | EP | disclosed |
| US-20250346585-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2025-11-13 | — | — | US | disclosed |
| US-12448395-B2 | Substituted bicyclic heteroaryl compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-10-21 | — | — | US | disclosed |
| EP-4573088-A1 | HETEROCYCLE RBM39 MODULATORS | Recursion Pharmaceuticals, Inc. (US) | 2025-06-25 | — | — | EP | disclosed |
| WO-2025045233-A1 | MACROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF | 劲方医药科技(上海)股份有限公司 | 2025-03-06 | — | — | WO | disclosed |
| CN-114761404-B | Substituted bicyclic heteroaryl compounds | 百时美施贵宝公司 | 2025-02-21 | — | — | CN | disclosed |
| WO-2025019407-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | PRETZEL THERAPEUTICS, INC. (US) | 2025-01-23 | — | — | WO | disclosed |
| US-20240124489-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2024-04-18 | — | — | US | disclosed |
| US-20240092770-A1 | Heterocycle RMB39 Modulators | RECURSION PHARMACEUTICALS, INC. | 2024-03-21 | — | — | US | disclosed |
| WO-2024039689-A1 | HETEROCYCLE RBM39 MODULATORS | RECURSION PHARMACEUTICALS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| US-20230139171-A1 | SYSTEM AND METHOD FOR INSTRUCTING ONE OR MORE WEATHER DRONES | SITA INFORMATION NETWORKING COMPUTING UK LIMITED (GB) | 2023-05-04 | — | — | US | disclosed |
| US-20230139171-A1 | SYSTEM AND METHOD FOR INSTRUCTING ONE OR MORE WEATHER DRONES | SITA INFORMATION NETWORKING COMPUTING UK LIMITED (GB) | 2023-05-04 | — | — | US | disclosed |
| US-20230139171-A1 | SYSTEM AND METHOD FOR INSTRUCTING ONE OR MORE WEATHER DRONES | SITA INFORMATION NETWORKING COMPUTING UK LIMITED (GB) | 2023-05-04 | — | — | US | disclosed |
| CN-115611895-A | Arylamino derivative estrogen receptor modulators and uses thereof | 四川海思科制药有限公司 | 2023-01-17 | — | — | CN | disclosed |
| EP-4041730-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | Bristol-Myers Squibb Company (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114761404-A | Substituted bicyclic heteroaryl compounds | 百时美施贵宝公司 | 2022-07-15 | — | — | CN | disclosed |
| WO-2021067326-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-04-08 | — | — | WO | disclosed |
| WO-2020030924-A1 | THIAZOLEUREAS AS ANTICANCER AGENTS | ARTIOS PHARMA LIMITED (GB) | 2020-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124489-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | TLR7, TLR1, TLR9 | LCK 205/4885PI4KB 1819/4885CA1 4425/4885 |
| US-20250346585-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | C5, C1S, C9 | LCK 2160/4885PI4KB 2306/4885CA1 4723/4885 |
| US-12448395-B2 | Substituted bicyclic heteroaryl compounds | TLR7, TLR1, TLR9 | LCK 205/4885PI4KB 1819/4885CA1 4425/4885 |
| US-20240092770-A1 | Heterocycle RMB39 Modulators | PRMT9, RCC2, RBBP9 | LCK 2679/4885PI4KB 1368/4885CA1 4867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.