Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 4/20 | 1.00 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 9/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.70 |
| ▸ | RAB9A | P51151 | 7/20 | 0.70 |
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | HTT | P42858 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | STAT3 | P40763 | 1/20 | 0.70 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.66 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.66 |
| ▸ | GFER | P55789 | 2/20 | 0.66 |
| ▸ | INSR | P06213 | 5/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845065 | 1.00 | KDM4A (1.00) | KDM4AKDM2AMEN1KMT2ARAB9A | |
| SCHEMBL14180797 | 1.00 | KDM4A (1.00) | KDM4AKDM2AMEN1KMT2ARAB9A | |
| SCHEMBL14180800 | 1.00 | KDM4A (1.00) | KDM4AKDM2AMEN1KMT2ARAB9A | |
| SCHEMBL10845067 | 1.00 | KDM4A (1.00) | KDM4AKDM2AMEN1KMT2ARAB9A | |
| SCHEMBL10847205 | 1.00 | KDM4A (1.00) | KDM4AKDM2AMEN1KMT2ARAB9A | |
| Bromide SCHEMBL10843057 | 0.99 | KDM4A (0.97) | KDM4AKDM2AMEN1KMT2ARAB9A | |
| Bromide SCHEMBL10845380 | 0.99 | KDM4A (0.97) | KDM4AKDM2AMEN1KMT2ARAB9A | |
| Iodide SCHEMBL4752505 | 0.99 | KDM4A (1.00) | KDM4AKDM2AMEN1KMT2ARAB9A | |
| Bromide SCHEMBL10845383 | 0.99 | KDM4A (0.97) | KDM4AKDM2AMEN1KMT2ARAB9A | |
| Bromide SCHEMBL10843063 | 0.99 | KDM4A (0.97) | KDM4AKDM2AMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4608379-A | TOPICAL ADMINISTERING | JOHN WYETH & BROTHER LIMITED (GB) | 1986-08-26 | — | — | US | claimed |
| EP-0139440-A2 | Pyridinium compounds | JOHN WYETH & BROTHER LIMITED (GB) | 1985-05-02 | — | — | EP | claimed |