Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | AKT1 | P31749 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | CDC25A | P30304 | 1/20 | 0.67 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.63 |
| ▸ | PRKCG | P05129 | 1/20 | 0.63 |
| ▸ | PRKCB | P05771 | 1/20 | 0.63 |
| ▸ | PRKCA | P17252 | 1/20 | 0.63 |
| ▸ | PRKCH | P24723 | 1/20 | 0.63 |
| ▸ | PRKCI | P41743 | 1/20 | 0.63 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.63 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.63 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845546 | 1.00 | LMNA (0.67) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL10847557 | 1.00 | LMNA (0.67) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL10847240 | 1.00 | LMNA (0.67) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL10850808 | 1.00 | LMNA (0.67) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL10847101 | 1.00 | LMNA (0.67) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL10848422 | 1.00 | LMNA (0.67) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL10846398 | 1.00 | LMNA (0.67) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL10846278 | 1.00 | LMNA (0.67) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL10847452 | 1.00 | LMNA (0.67) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL10845565 | 1.00 | LMNA (0.67) | LMNAAKT1ESR1ADORA3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4610979-A | O-acyl-alkanediol-phospholipids and processes for the treatment of asthma | A. NATTERMANN & CIE GMBH (DE) | 1986-09-09 | — | — | US | disclosed |