Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10848465 | 1.00 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL24704162 | 0.80 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL24704152 | 0.80 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL4818718 | 0.79 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4818722 | 0.79 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8525580 | 0.78 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL8525581 | 0.78 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL24704158 | 0.77 | NR4A1 (0.47) | MAPTKMT2AALDH1A1PLK1HPGD | |
| SCHEMBL10773921 | 0.75 | CNR2 (0.45) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL10773918 | 0.75 | CNR2 (0.45) | PDE4APDE4BPDE4CPDE4DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4568377-A | IMPROVED CROP SAFETY | CHEVRON RESEARCH COMPANY (US) | 1986-02-04 | — | — | US | disclosed |