Hydroxystilbamidine

Hydroxystilbamidine

SCHEMBL108492

N=C(N)c1ccc(/C=C/c2ccc(C(=N)N)cc2O)cc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.72
POLB P06746 1/20 0.72
MAPT P10636 1/20 0.72
RAD52 P43351 1/20 0.72
UBE2N P61088 1/20 0.72
NPSR1 Q6W5P4 1/20 0.72
PRMT1 Q99873 3/20 0.66
PRMT5 O14744 1/20 0.66
ALDH1A1 P00352 1/20 0.66
HPGD P15428 1/20 0.66
CYP2C19 P33261 1/20 0.66
HSD17B10 Q99714 1/20 0.66
PLAU P00749 5/20 0.51
PLG P00747 2/20 0.51
PLAT P00750 2/20 0.51
KLK1 P06870 2/20 0.51
NQO2 P16083 1/20 0.48
LMNA P02545 1/20 0.44
KDM1A O60341 3/20 0.43
SYNJ2 O15056 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxystilbamidine SCHEMBL29439031 1.00 KDM4E (0.72) KDM4EPOLBMAPTRAD52UBE2N
Hydroxystilbamidine SCHEMBL8482349 1.00 KDM4E (0.72) KDM4EPOLBMAPTRAD52UBE2N
Hydroxystilbamidine SCHEMBL31614578 1.00 KDM4E (0.72) KDM4EPOLBMAPTRAD52UBE2N
Hydroxystilbamidine SCHEMBL27618664 0.95 KDM4E (0.67) KDM4EPOLBMAPTRAD52UBE2N
SCHEMBL14541861 0.91 KDM4E (0.62) KDM4EPOLBMAPTRAD52UBE2N
SCHEMBL14340159 0.90 KDM4E (0.61) KDM4EPOLBMAPTRAD52UBE2N
Hydroxystilbamidine SCHEMBL26114123 0.90 KDM4E (0.77) KDM4EPOLBMAPTRAD52UBE2N
Hydroxystilbamidine SCHEMBL3338013 0.90 KDM4E (0.77) KDM4EPOLBMAPTRAD52UBE2N
Hydroxystilbamidine SCHEMBL17224190 0.90 KDM4E (0.77) KDM4EPOLBMAPTRAD52UBE2N
SCHEMBL14437186 0.88 KDM4E (0.63) KDM4EPOLBMAPTRAD52UBE2N

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3087 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260069175-A1 SAMPLE-TO-ANSWER DIAGNOSTIC SYSTEM FOR THE DETECTION OF CIRCULATING HISTONES IN WHOLE BLOOD UNIV MARYLAND (US) 2026-03-12 US claimed
US-12551149-B2 Sample-to-answer diagnostic system for the detection of circulating histones in whole blood UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2026-02-17 US claimed
US-20230390405-A1 SELECTIVE NERVE CELL DEACTIVATION EXODUS TECHNOLOGY LTD. (IL) 2023-12-07 US claimed
EP-4244340-A1 SELECTIVE NERVE CELL DEACTIVATION Tsuriel, Shlomo (IL) 2023-09-20 EP claimed
WO-2023164252-A1 ISOTHERMAL NUCLEIC ACID DETECTION ASSAYS AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-08-31 WO claimed
US-20230063411-A1 SAMPLE-TO-ANSWER DIAGNOSTIC SYSTEM FOR THE DETECTION OF CIRCULATING HISTONES IN WHOLE BLOOD UNIVERSITY OF MARYLAND, COLLEGE PARK 2023-03-02 US claimed
WO-2022101907-A1 SELECTIVE NERVE CELL DEACTIVATION TSURIEL SHLOMO (IL) 2022-05-19 WO claimed
WO-2019051106-A1 DETECTION AND IDENTIFICATION OF BACTERIA AND DETERMINATION OF ANTIBIOTIC SUSCEPTIBILITY USING BACTERIOPHAGE AND REPORTER MOLECULES THE CHARLES STARK DRAPER LABORATORY INC. (US) 2019-03-14 WO claimed
US-20190078133-A1 DETECTION AND IDENTIFICATION OF BACTERIA AND DETERMINATION OF ANTIBIOTIC SUSCEPTIBILITY USING BACTERIOPHAGE AND REPORTER MOLECULES CHARLES STARK DRAPER LABORATORY INC (US) 2019-03-14 US claimed
CN-109342381-A A kind of fluorescent dyeing reagent 广州往圣生物科技有限公司 2019-02-15 CN claimed
EP-1339399-A2 COMBINATIONS OF DRUGS (E.G., CHLORPROMAZINE AND PENTAMIDINE) FOR THE TREATMENT OF NEOPLASTIC DISORDERS Combinatorx, Incorporated (US) 2003-09-03 EP claimed
US-20020165261-A1 Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders ZALICUS INC. 2002-11-07 US claimed
WO-2002081739-A2 NON-ENZYMATIC LIPOSOME-LINKED CLOSELY SPACED ARRAY ELECTRODES ASSAY (NEL-ELA) FOR DETECTING AND QUANTIFYING NUCLEIC ACIDS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2002-10-17 WO claimed
WO-2002058684-A2 COMBINATIONS OF DRUGS (E.G., CHLORPROMAZINE AND PENTAMIDINE) FOR THE TREATMENT OF NEOPLASTIC DISORDERS COMBINATORX, INCORPORATED (US) 2002-08-01 WO claimed
WO-2002058697-A1 COMBINATIONS OF DRUGS (E.G., A BENZIMIDAZOLE AND PENTAMIDINE) FOR THE TREATMENT OF NEOPLASTIC DISORDERS COMBINATORX, INCORPORATED (US) 2002-08-01 WO claimed
US-20020072053-A1 Immunoassay based on DNA replication using labeled primer ROCHE DIAGNOSTICS OPERATIONS, INC. 2002-06-13 US claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-0316440-B1 System and method for providing localized Mössbauer absorption in an organic medium MILLS RANDELL L (US) 1996-01-03 EP claimed