Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10887686 | 0.91 | PDE3B (0.46) | PDE3BPDE3ARAB9ANPC1POLB | |
| SCHEMBL10885868 | 0.90 | PDE3B (0.45) | PDE3BPDE3ARAB9ANPC1POLB | |
| SCHEMBL10849673 | 0.86 | PDE3B (0.45) | PDE3BPDE3AALDH1A1PDE4APDE4B | |
| SCHEMBL10886403 | 0.86 | PDE3B (0.45) | PDE3BPDE3AALDH1A1PDE4APDE4B | |
| SCHEMBL10636413 | 0.85 | PDE3B (0.64) | PDE3BPDE3APOLBALDH1A1GAA | |
| SCHEMBL10888365 | 0.84 | PDE3B (0.47) | PDE3BPDE3APOLBALDH1A1PDE4A | |
| SCHEMBL10891566 | 0.83 | GPR119 (0.43) | PDE3BPDE3APOLBALDH1A1GAA | |
| SCHEMBL10887832 | 0.83 | PDE3B (0.51) | PDE3BPDE3AALDH1A1PDE4APDE4B | |
| SCHEMBL10633041 | 0.83 | PDE3B (0.48) | PDE3BPDE3APOLBALDH1A1PDE4A | |
| SCHEMBL10846981 | 0.82 | GPR119 (0.47) | PDE3BPDE3ARAB9ANPC1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618610-A | Triazine derivatives, and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| EP-0123254-A1 | Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |