Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.81 |
| ▸ | PTAFR | P25105 | 1/20 | 0.81 |
| ▸ | HTR1D | P28221 | 1/20 | 0.81 |
| ▸ | HTR2C | P28335 | 1/20 | 0.81 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.81 |
| ▸ | DRD3 | P35462 | 1/20 | 0.81 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.64 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | AKT1 | P31749 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | GMNN | O75496 | 2/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10852722 | 1.00 | ADRA1D (0.81) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10846439 | 1.00 | ADRA1D (0.81) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10847644 | 1.00 | ADRA1D (0.81) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10846630 | 1.00 | ADRA1D (0.81) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10844793 | 1.00 | ADRA1D (0.81) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| Platelet Activating Factor SCHEMBL2734461 | 0.89 | ADRA1D (1.00) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10920867 | 0.89 | ADRA1D (0.65) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10921755 | 0.89 | ADRA1D (0.65) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10924112 | 0.89 | ADRA1D (0.65) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10917222 | 0.89 | ADRA1D (0.65) | ADRA1DPTAFRHTR1DHTR2CADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121088-B1 | NEW O-ACYL-ALKANEDIOL-PHOSPHOLIPIDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | A. Nattermann & Cie. GmbH (DE) | 1986-10-01 | — | — | EP | disclosed |
| US-4610979-A | O-acyl-alkanediol-phospholipids and processes for the treatment of asthma | A. NATTERMANN & CIE GMBH (DE) | 1986-09-09 | — | — | US | disclosed |